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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRRT All Species: 18.79
Human Site: S580 Identified Species: 41.33
UniProt: Q9BXP5 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BXP5 NP_001122324.1 876 100666 S580 E E E L L G S S G G A P P E E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001106640 860 98726 S580 E E E L L G S S G G A P P E E
Dog Lupus familis XP_536858 879 101306 S595 E E E L L G S S G G A P P E E
Cat Felis silvestris
Mouse Mus musculus Q99MR6 875 100434 S579 E E E L L G S S G G P P P E E
Rat Rattus norvegicus XP_001076594 762 87510 N496 E G N P A E I N V E R D E K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis B1H1X4 849 98562 E572 A G R T P E T E L P K D G N P
Zebra Danio Brachydanio rerio Q66I22 896 103255 A611 E E E L L G S A G G G D S E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9K7 943 107203 T688 E E E L L G L T G E N K D T E
Honey Bee Apis mellifera XP_396542 894 101991 S639 E E E L L G M S G D Q E E G Q
Nematode Worm Caenorhab. elegans Q966L5 712 80776 N477 V H S I D F Y N H G H Y A Q E
Sea Urchin Strong. purpuratus XP_787830 934 107085 K649 E E V L L G M K A D G Q E E G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.8 96.8 N.A. 97.7 84.9 N.A. N.A. N.A. 69.8 70.4 N.A. 42.2 48.4 37.5 46.4
Protein Similarity: 100 N.A. 97 97.6 N.A. 98.7 85.8 N.A. N.A. N.A. 81.3 80.4 N.A. 57.6 65.5 52 60.9
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 6.6 N.A. N.A. N.A. 0 66.6 N.A. 53.3 53.3 13.3 40
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 20 N.A. N.A. N.A. 6.6 80 N.A. 60 60 33.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 10 0 0 10 10 0 28 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 19 0 28 10 0 10 % D
% Glu: 82 73 64 0 0 19 0 10 0 19 0 10 28 55 55 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 19 0 0 0 73 0 0 64 55 19 0 10 10 10 % G
% His: 0 10 0 0 0 0 0 0 10 0 10 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 10 10 0 10 0 % K
% Leu: 0 0 0 73 73 0 10 0 10 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 19 0 0 10 0 0 10 0 % N
% Pro: 0 0 0 10 10 0 0 0 0 10 10 37 37 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 10 0 10 10 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 0 10 0 0 0 46 46 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 10 0 0 10 10 0 0 0 0 0 10 0 % T
% Val: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _